Bone Density Research

Diets high in saturated fat can make it difficult for the body to absorb calcium, which adversely affects bone growth. Strong bones provide a solid foundation for good health. Conversely, low bone mass can lead to osteoporosis, which translates to a reduction in bone mass and increased susceptibility to fractures.

Compounding this problem is the fact that some treatments for diseases attributed to consumption of high-fat diets can actually hamper the body’s ability to build strong bones. In particular, rosiglitazone (also known as Avandia), a drug used to lower glucose in patients with type 2 diabetes, is associated with increased risk of osteoporosis.

Because mangos have been effective in reducing body fat accumulation in mice fed a high-fat diet, the National Mango Board commissioned a research study to examine the effect of mangos on bone parameters in mice fed a high-fat diet. In mice, consumption of mangos helped to counteract the negative effects on bone parameters caused by a high-fat diet. Mangos have been shown to improve glucose levels in mice without the side effects of bone loss that are associated with taking rosiglitazone.

Check out the report below for the complete details, and stay tuned for the results of the NMB’s current study investigating the impact of mango on bone parameters in Ovariectomized mice, a model of osteoporosis in postmenopausal women.

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